GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs60843830 | 1 | rs79716074 | chr2:277003 | SH3YL1 | chr2:218138-264810:- | -0.45 | -11.81 | 1.2E-27 | Spherical equivalent (joint main effects and education interaction) |
| BLCA | cis | rs6951245 | 1 | rs79765398 | chr7:1073764 | ZFAND2A | chr7:1192544-1199855:- | -0.37 | -4.35 | 1.78E-5 | C-reactive protein levels or total cholesterol levels (pleiotropy) |
| BLCA | cis | rs7980687 | 1 | rs7980687 | chr12:123822711 | ABCB9 | chr12:123413540-123459752:- | 0.32 | 3.96 | 8.78E-5 | Educational attainment;Height;Head circumference (infant) |
| BLCA | cis | rs7980687 | 1 | rs7980687 | chr12:123822711 | CDK2AP1 | chr12:123745542-123756687:- | -0.34 | -4.76 | 2.76E-6 | Educational attainment;Height;Head circumference (infant) |
| BLCA | cis | rs798766 | 1 | rs798719 | chr4:1698183 | FAM53A | chr4:1641609-1685854:- | -0.32 | -4.63 | 4.99E-6 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798724 | chr4:1704643 | FAM53A | chr4:1641609-1685854:- | -0.29 | -4.29 | 2.3E-5 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798741 | chr4:1712413 | FAM53A | chr4:1641609-1685854:- | -0.29 | -4.26 | 2.54E-5 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798744 | chr4:1714684 | FAM53A | chr4:1641609-1685854:- | -0.35 | -5.06 | 6.58E-7 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798754 | chr4:1720757 | FAM53A | chr4:1641609-1685854:- | -0.33 | -4.94 | 1.16E-6 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798755 | chr4:1720824 | FAM53A | chr4:1641609-1685854:- | -0.33 | -4.93 | 1.22E-6 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798756 | chr4:1707447 | FAM53A | chr4:1641609-1685854:- | -0.32 | -4.57 | 6.73E-6 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798762 | chr4:1731150 | FAM53A | chr4:1641609-1685854:- | -0.31 | -4.58 | 6.42E-6 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798766 | chr4:1734239 | FAM53A | chr4:1641609-1685854:- | 0.31 | 4.55 | 7.06E-6 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs798766 | 1 | rs798767 | chr4:1734281 | FAM53A | chr4:1641609-1685854:- | -0.32 | -4.7 | 3.62E-6 | Urinary bladder cancer;Bladder cancer |
| BLCA | cis | rs7327064 | 1 | rs7995669 | chr13:36762986 | SOHLH2 | chr13:36742347-36871992:- | -0.39 | -5.08 | 6.03E-7 | Economic and political preferences |